Declared serrapeptase activity per capsule. One capsule is one serving.
250,000 SPU. Per Capsule.
iSerra declares 250,000 SPU of serrapeptase activity in each capsule, with one capsule as one serving. Delivery architecture, finished-product testing, and lot-specific verification provide the context behind the number.
SPU measures enzyme activity. It is different from milligrams, and a declared activity specification is different from a measured result for a specific lot.

Don’t stop at the number on the label.
250,000 SPU is the declared activity specification per capsule. iSerra keeps that specification separate from the measured activity result for the current shipping lot—and connects the lot to a verification record.
Measured activity reported for current shipping Lot 6798.
Veriphase™ connects the production lot to its available lot-specific record.
Measured activity is specific to the production lot assayed and is not a guarantee that every future lot will produce the same measured result. The labeled specification remains 250,000 SPU per capsule.
250,000 SPU is meaningful when the serving context is clear.
iSerra states activity per capsule and uses a one-capsule serving. The Supplement Facts also show ingredient weight separately so SPU and milligrams are not treated as interchangeable measurements.
Supplement Facts
Serving Size 1 Capsule · Servings Per Container 90
(Serratiopeptidase enzyme)130 mg
250,000 SPU
130 mg and 250,000 SPU describe different things.
Milligrams describe ingredient weight. SPU describes serrapeptase enzyme activity. Both are useful disclosures, but they should not be compared as if they were the same measurement.
The label sets the specification. The lot record shows what was measured.
The product is declared at 250,000 SPU per capsule. A measured activity result belongs to the production lot that was assayed and should not be silently converted into a claim for every future lot.
Production lots change. The lot printed on the bottle is the authoritative lookup key.
Three other questions complete the comparison.
Activity is only one disclosure layer. Delivery architecture, finished-product testing, and bottle-lot traceability provide different context.
Bilamex™ Dual-Phase Delivery
A delayed-release capsule plus coated enzyme-containing particles creates two disclosed physical stages.
SEE THE DELIVERY TECHNOLOGY →Apply the same four criteria
Use activity, delivery architecture, finished-product testing, and traceability for a consistent comparison.
VIEW THE EVIDENCE GUIDE →Verify the bottle lot
Connect the lot on a physical bottle to its applicable available verification record.
VERIFY A LOT →Keep the activity assay separate from the delivery observation.
Lot 6798 was separately evaluated under USP <2040> finished-product disintegration testing. This is a dosage-form observation, not the activity assay and not a clinical outcome.
Reference Lot 6798 · tested August 5, 2026. Do not generalize the 60/37-minute observations to every production lot.
No disintegration through 60 minutes.
Complete disintegration at 37 minutes.
The distinctions worth keeping clear.
What does 250,000 SPU mean?
SPU is a measure of serrapeptase enzyme activity. iSerra declares 250,000 SPU per capsule in a one-capsule serving.
Is 250,000 SPU the same thing as 130 mg?
No. 130 mg describes ingredient weight; 250,000 SPU describes declared enzyme activity.
Why can a lot show a different measured SPU result?
The label states the declared specification. A laboratory assay reports the measured activity of the specific production lot tested.
How can I verify my bottle?
Use the production lot printed on the bottle at the Verify Your Lot page.

Choose 250,000 SPU per capsule with more context behind the label.
250,000 SPU per capsule · Bilamex™ Dual-Phase Delivery · finished-product testing · Veriphase™ lot-specific verification.